Thursday, June 15, 2023 (HealthDay News) — Having inflammatory bowel disease (IBD) may increase your long-term risk of stroke, according to new research.
Researchers found that people with IBD were 13% more likely to have a stroke within 25 years of diagnosis than those without.Their report was published in the magazine on June 14th. Neurology.
“These results indicate that people with inflammatory bowel disease and their physicians should be aware of this long-term increased risk,” said study co-authors. Sun Jiang Weiof the Karolinska Institutet in Stockholm, Sweden.
“Screening and management of stroke risk factors may be more urgent for patients with IBD,” Sun added in the journal’s news release.
The findings do not prove that IBD causes this serious outcome, only that it is relevant.
Types of IBD include Crohn’s disease, which causes chronic inflammation of the intestine, ulcerative colitis, and unclassified inflammatory bowel disease.
The study included more than 85,000 people with biopsy-confirmed IBD. Each subject was matched with up to five individuals of the same age, sex, and residence who did not have IBD. There were about 407,000 people in the control group.
Among study participants, 3,720 IBD patients developed a stroke during a mean follow-up period of 12 years. By comparison, the 15,599 people without IBD who had a stroke belonged to a much larger group.
The incidence of stroke was 32.6 per 10,000 person-years in patients with IBD compared with 27.7 in patients without IBD. Person-years represent both the number of people who participated in the study and the time each person spent on the study.
The increased risk was primarily ischemic stroke, the most common type caused by blockage of blood flow to the brain. Hemorrhagic stroke is caused by bleeding in the brain.
Both IBD and stroke have some genetic component that predisposes people to the disease, the study authors noted. For this reason, the study also included full siblings of IBD patients. At the start of the study, more than 101,000 siblings had no history of IBD or stroke.
Those with IBD remained at higher risk of stroke than their siblings without IBD. Their overall risk was 11% higher for him.
“The increased risk for people with IBD remains 25 years after initial diagnosis, which equates to one additional stroke for every 93 people with IBD up to that point,” Sun said. .
The authors cautioned that diagnostic criteria for IBD and stroke have changed over the years, which could affect the results. The data also did not include complete information on all factors that could influence stroke risk, including diet, smoking and alcohol consumption, which was a limitation of the study.
For more information
The U.S. Centers for Disease Control and Prevention provides further information. inflammatory bowel disease.
sauce: neurologyNews Release, June 14, 2023
