A Yale University study released Wednesday found that sustained levels of spike protein in the Covid-19 vaccine could be associated with a range of chronic symptoms, such as excessive fatigue, brain fog and muscle pain.
study These and other symptoms (such as tingling and numbness, exercise intolerance, difficulty in concentration) are described as post-vaccine syndromes or PVS. Other symptoms included problems with falling or sleeping, nerve damage, muscle pain, anxiety, tinnitus and burning sensations. This study was published as a preprint. This means that they have not yet found a home in a scientific journal and have not yet been reviewed by external scientists through peer review.
Researcher We studied 42 individuals They were diagnosed with PVS. Researchers used serology or blood tests to test numerous potential biological features of the syndrome, revealing various hypotheses about the underlying causes.
The researchers hesitated to identify one single cause and emphasized the need for further research.
But perhaps the most impressive The cues were significantly higher circulating levels of spike protein compared to the control group. Individuals who received vaccinations 600-700 days ago had higher levels of spike protein than other participants who were recently vaccinated.
However, in this study, only the spike protein levels of each individual were measured once; Could not decide Whether the spike protein increases over time.
“This suggests that long-term antigen persistence may be associated with PVS in subgroups of patients,” the study reads.
Our prelint regarding post-vaccination syndrome is out. We studied the immune signature and examined the spike proteins in the blood of people who developed chronic diseases after receiving a Covid-19 vaccine. (1/) https://t.co/mc5dfhyryf
– Professor Ikeko (@virusesimmunity) February 20, 2025
This study included participants who received shots of Pfizer, Moderna, Johnson & Johnson.
Another potential signal of the syndrome investigated in the paper is T cell fatigue – When white blood cells gradually lose their ability to fight infections. People with PVS had fewer antibodies to the spike protein compared to the control group. Syndromes may also be associated with reactivation of dormant status Epstein Barr virus (EBV), a common and usually potential virus.
Researchers acknowledged that PVS has been ignored by health authorities as many consider the topic “radioactive.”
“This is a difficult topic to study. People don’t want to fund it, and the journal doesn’t want to publish it because it is considered radioactive, and I have maintained the course as well as I have maintained its course. I am very grateful to the author.” Co-authors of Mount Sinai Health System and paper; x Thread. “If you’re saying that this paper burns anti-Bucks moves, think about it for a moment: you can’t be transparent at that moment, you can deny many living experiences and hide the truth. It hinders the anti-science movement. In the history of drug discovery, there has never been a drug in the proportion of users that does not cause side effects. It is dishonest to pretend that this is not real.”
Anti-science movement. In the history of drug discovery, no drug in the proportion of users has caused no side effects. It is dishonest that pretending this fact is not realistic. The people who are trying to hide, deny or shame people in PVS are their existence 15/
– Putrino Lab (@putrinolab) February 19, 2025
However, some of the science community Criticized scientists To make the preprints public at all.
This study presented data from Yale School of Medicine. Listen to (hear) current immunity, symptoms and treatment experiences and is a post-covid care center at Mount Sinai Hospital.
The PVS group had lower health and quality of life than average despite lacking pre-existing comorbidities in the cohort and being relatively young (median age 43 years).
Long Covid shares many of the same symptoms of PVS, the researchers wrote, but there are some differences. Although long Covid may be associated with elevated SARS-COV-2 antibodies, individuals with PVS in new studies had lower antibodies than controls.
Preprint says the condition is causing some people receiving the Covid-19 vaccine. Researchers quickly highlighted that the Covid-19 vaccine saved lives.
“By revealing distinct immunological features of PVS, this study helped to generate hypotheses regarding the underlying pathobiology of this condition,” the study reads. “Understanding such mechanisms will help to improve the overall safety profile of Covid-19 vaccines and support public health strategies that maximize vaccine efficacy while minimizing side effects. Masu.”
This study arrives in Robert F. Kennedy Jr. First day at Helm Ministry of Health and Human Services.
His ascension to the role of HHS secretary has resulted in policies promulgated by the Biden administration on Covid-19 vaccines, including a decision to mandate vaccinations of some individuals with the previous Covid-19 infection as a prerequisite for employment. I was able to reconsider it.
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